anti-CD29 (human), Rabbit Monoclonal (RM285) - 深圳欣博盛生物科技有限公司

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anti-CD29 (human), Rabbit Monoclonal (RM285)

品牌： Adipogen

产品货号： REV-31-1169-00-R100

规格： 100 µl

报价：

折后价：

数量： - +

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产品名称:

anti-CD29 (human), Rabbit Monoclonal (RM285)
别名:

Integrin beta-1; Fibronectin Receptor Subunit beta; Glycoprotein 2a; VLA-4 Subunit beta
产品描述:

Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions. CD29 (ITGB1; Integrin Subunit Beta 1; beta1 integrin subunit; GPIIa) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins. CD29 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. Decreased expression of CD29 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug. CD29 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue. Further, CD29 also regulates tissue damage and disease symptoms related to inflammatory bowel disease.
反应种属:
宿主来源:

Rabbit
实验应用:

IHC, WB
靶标/特异性:
同种型:

Rabbit IgG
推荐稀释度:
免疫原:

A peptide corresponding to the residues in human CD29 (Integrin beta-1). .
免疫原种属:
克隆性:
克隆号:

RM285
纯化方式:
偶联:
产品浓度:
表达系统:
阳性对照:
保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:
产品形式:

liquid
存储溶液:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
有效期:

Stable for at least 1 year after receipt when stored at -20°C.
产地:

瑞士
外观:
生产商:
功能与背景:
URL:
灵敏度:
检测范围:
检测方法:
样本类型:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产品特点:
纯度:

Protein A purified.
生物活性:
内毒素水平:
来源:
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Accession #:
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PubChem CID: