anti-LC3B (human), Rabbit Monoclonal (RM293) - 深圳欣博盛生物科技有限公司

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anti-LC3B (human), Rabbit Monoclonal (RM293)

品牌： Adipogen

产品货号： REV-31-1177-00-R100

规格： 100 µl

报价：

折后价：

数量： - +

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产品名称:

anti-LC3B (human), Rabbit Monoclonal (RM293)
别名:

Autophagy-related Protein LC3 B; Microtubule-associated Proteins 1A/1B Light Chain 3B; MAP1A/MAP1B LC3 B
产品描述:

LC3 is a central protein in the autophagy pathway where it functions in autophagy substrate selection and autophagosome biogenesis. It is the most widely used marker of autophagosomes. Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. LC3B (Autophagy Marker Light Chain 3B; MAP1A/MAP1B LC3 B) is associated with microtubule assembly and important in neurogenesis. LC3B plays a vital role in autophagy, a process that involves the bulk degradation of cytoplasmic component. Three human LC3 isoforms undergo post-translational modifications during autophagy. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). LC3B is a microtubule-associated protein that mediate the physical interactions between microtubules and components of the cytoskeleton. LC3B may play a role in processes involving cancer, aging, metabolic and neurodegenerative disorders and cardiovascular/pulmonary diseases.
反应种属:
宿主来源:

Rabbit
实验应用:

ICC, IHC, WB
靶标/特异性:
同种型:

Rabbit IgG
推荐稀释度:
免疫原:

A peptide corresponding to the N-terminus of human LC3B.
免疫原种属:
克隆性:
克隆号:

RM293
纯化方式:
偶联:
产品浓度:
表达系统:
阳性对照:
保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:
产品形式:

liquid
存储溶液:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
有效期:

Stable for at least 1 year after receipt when stored at -20°C.
产地:

瑞士
外观:
生产商:
功能与背景:
URL:
灵敏度:
检测范围:
检测方法:
样本类型:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产品特点:
纯度:

Protein A purified.
生物活性:
内毒素水平:
来源:
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Accession #:
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PubChem CID: