anti-Phospho-AMPA Receptor (Ser845) (human), Rabbit Monoclonal (RM296)

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品牌： Adipogen

产品货号： REV-31-1179-00-R100

规格： 100 µl

报价：

折后价：

数量： - +

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产品名称:

anti-Phospho-AMPA Receptor (Ser845) (human), Rabbit Monoclonal (RM296)
别名:

Glutamate Receptor 1; GluR 1; GluA1; GluR-A; GluR-K1
产品描述:

AMPA receptors (AMPARs) are heterotetrameric complexes composed of subunits GluR1–4, each of them conferring specific properties on the active receptor, including trafficking motifs, which is related to synaptic plasticity. These glutamate receptors are responsible for the fast, immediate postsynaptic response to glutamate release. Therefore, the receptor–channel complex, predominantly permeable for sodium and potassium ions, activates fast and shows rapid desensitization. AMPA receptors are abundant and widely distributed in the central nervous system. GluR1 (Glutamate Receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Phosphorylation of GluR1 is critical for long-term potentiation (LTP) and long-term depression (LTD) expression and the retention of memories.
反应种属:
宿主来源:

Rabbit
实验应用:

IHC, WB
靶标/特异性:
同种型:

Rabbit IgG
推荐稀释度:
免疫原:

A phospho-peptide corresponding to human Phospho-Glutamate Receptor 1 (GluR1) (Ser845).
免疫原种属:
克隆性:
克隆号:

RM296
纯化方式:
偶联:
产品浓度:
表达系统:
阳性对照:
保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:
产品形式:

liquid
存储溶液:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
有效期:

Stable for at least 1 year after receipt when stored at -20°C.
产地:

瑞士
外观:
生产商:
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URL:
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样本类型:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产品特点:
纯度:

Protein A purified.
生物活性:
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