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anti-CD79a (C-term) (human), Rabbit Monoclonal (RM297)
品牌: Adipogen
产品货号: REV-31-1182-00-R100
规格: 100 µl

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    anti-CD79a (C-term) (human), Rabbit Monoclonal (RM297)
  • 别名:
    B-cell Antigen Receptor Complex-associated Protein alpha Chain; Membrane-bound Immunoglobulin-associated Protein
  • 产品描述:
    CD79a is a disulphide-linked heterodimer together with CD79b. CD79a plays multiple and diverse roles in B cell development and function. The CD79a/b heterodimer associates non-covalently with the immunoglobulin heavy chain through its transmembrane region, thus forming the BCR along with the immunoglobulin light chain and the pre-BCR when associated with the surrogate light chain in developing B cells. Association of the CD79a/b heterodimer with the immunoglobulin heavy chain is required for surface expression of the BCR and BCR induced calcium flux and protein tyrosine phosphorylation. The CD79a protein is present on the surface of B-cells throughout their life cycle, and is absent on all other healthy cells, making it a highly reliable marker for B-cells in immunohistochemistry. The protein remains present when B cells transform into active plasma cells, and is also present in virtually all B-cell neoplasms, including B-cell lymphomas, plasmacytomas and myelomas. It is also present in abnormal lymphocytes associated with some cases of Hodgkins disease. Because even on B cell precursors, it can be used to stain a wider range of cells compared to the alternative B cell marker CD20 and is often used together in immunohistochemistry panels.
  • 反应种属:
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC, WB
  • 靶标/特异性:
  • 同种型:
    Rabbit IgG
  • 推荐稀释度:
  • 免疫原:
    A peptide corresponding to the C-terminus of human CD79a.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    RM297
  • 纯化方式:
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
  • 产品特点:
  • 纯度:
    Protein A purified.
  • 生物活性:
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