anti-MyoD1 (human), Rabbit Monoclonal (RM369) - 深圳欣博盛生物科技有限公司

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anti-MyoD1 (human), Rabbit Monoclonal (RM369)

品牌： Adipogen

产品货号： REV-31-1255-00-R100

规格： 100 µl

报价：

折后价：

数量： - +

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产品名称:

anti-MyoD1 (human), Rabbit Monoclonal (RM369)
别名:

Myoblast Determination Protein 1; Class C Basic Helix-loop-helix Protein 1; bHLHc1; Myf-3
产品描述:

MyoD (MyoD1; Myoblast Determination Protein 1) plays a major role in regulating muscle differentiation. It belongs to a family of proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. Vertebrate MRF family members include MyoD1, Myf5, myogenin and MRF4 (Myf6). MyoD is one of the earliest markers of myogenic commitment. MyoD is expressed at extremely low and essentially undetectable levels in quiescent satellite cells, but expression of MyoD is activated in response to exercise or muscle tissue damage. High MyoD expression represses cell renewal, promotes terminal differentiation and can induce apoptosis. The function of MyoD in development is to commit mesoderm cells to a skeletal myoblast lineage, and then to regulate that continued state. MyoD may also regulate muscle repair. MyoD mRNA levels are also reported to be elevated in aging skeletal muscle. One of the main actions of MyoD is to remove cells from the cell cycle (halt proliferation for terminal cell cycle arrest in differentiated myocytes) by enhancing the transcription of p21 and myogenin. MyoD, as a transcription factor, can also direct chromatin remodelling through binding to a DNA motif known as the E-box.
反应种属:
宿主来源:

Rabbit
实验应用:

IHC, WB
靶标/特异性:
同种型:

Rabbit IgG
推荐稀释度:
免疫原:

A peptide corresponding to residues near N-terminus of human MyoD1 (Myoblast determination protein 1).
免疫原种属:
克隆性:
克隆号:

RM369
纯化方式:
偶联:
产品浓度:
表达系统:
阳性对照:
保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:
产品形式:

liquid
存储溶液:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
有效期:

Stable for at least 1 year after receipt when stored at -20°C.
产地:

瑞士
外观:
生产商:
功能与背景:
URL:
灵敏度:
检测范围:
检测方法:
样本类型:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产品特点:
纯度:

Protein A purified.
生物活性:
内毒素水平:
来源:
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