anti-MPO (human), Rabbit Monoclonal (RM407) - 深圳欣博盛生物科技有限公司

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anti-MPO (human), Rabbit Monoclonal (RM407)

品牌： Adipogen

产品货号： REV-31-1293-00-R100

规格： 100 µl

报价：

折后价：

数量： - +

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产品名称:

anti-MPO (human), Rabbit Monoclonal (RM407)
别名:

Myeloperoxidase
产品描述:

Myeloperoxidase (MPO) is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains and two unglycosylated beta chains. Traditionally, myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities such as periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-myeloperoxidase autoantibody levels are also reported in rheumatoid arthritis. Myeloperoxidase also participates in the initiation and progression of cardiovascular disease and is a promising cardiac markers. Myeloperoxidase possesses potent proinflammatory properties and may contribute directly to tissue injury. Myeloperoxidase is part of the host defense system of polymorphonuclear leukocytes and myeloperoxidase is responsible for microbicidal activity against a wide range of organisms. In stimulated PMN (polymorphonuclear leukocytes), MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Myeloperoxidase immunostaining is important in the diagnosis of myeloid sarcoma, contrasting with the negative staining of lymphomas.
反应种属:
宿主来源:

Rabbit
实验应用:

IHC, WB
靶标/特异性:
同种型:

Rabbit IgG
推荐稀释度:
免疫原:

A peptide corresponding to the internal region of light chain on MPO. This antibody may also react to mouse or rat MPO, as predicted by immunogen homology.
免疫原种属:
克隆性:
克隆号:

RM407
纯化方式:
偶联:
产品浓度:
表达系统:
阳性对照:
保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:
产品形式:

liquid
存储溶液:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
有效期:

Stable for at least 1 year after receipt when stored at -20°C.
产地:

瑞士
外观:
生产商:
功能与背景:
URL:
灵敏度:
检测范围:
检测方法:
样本类型:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产品特点:
纯度:

Protein A purified.
生物活性:
内毒素水平:
来源:
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PubChem CID: