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anti-ZAP70 (human), Rabbit Monoclonal (RM408)
品牌： Adipogen
产品货号： REV-31-1294-00-R100
规格： 100 µl

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-ZAP70 (human), Rabbit Monoclonal (RM408)
  • 别名:
    Tyrosine-protein Kinase ZAP-70; 70 kDa zeta-chain Associated Protein; Syk-related Tyrosine Kinase
  • 产品描述:
    ZAP70 is a member of the Syk tyrosine kinase family and plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Upon T cell antigen receptor (TCR) engagement, ZAP70 is phosphorylated on tyrosines 292, 315 and 319 in the interdomain B, located between the SH2 and kinase domains. Phosphorylation of both tyrosines 315 (a Vav binding site) and 319 (a Lck binding site) enhances ZAP70 function in mediating lymphocyte signaling, while tyrosine 292 terminates the transient activation of ZAP70 and attentuates lymphocyte signaling. ZAP-70 in B cells is used as a prognostic marker in identifying different forms of chronic lymphocytic leukemia (CLL). In systemic lupus erythematosus, the Zap-70 receptor pathway is missing and Syk takes its place.
  • 反应种属:
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC, WB
  • 靶标/特异性:
  • 同种型:
    Rabbit IgG
  • 推荐稀释度:
  • 免疫原:
    A peptide corresponding to residues near the N-terminus of human ZAP70.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    RM408
  • 纯化方式:
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
  • 产品特点:
  • 纯度:
    Protein A purified.
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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