anti-CD25 (human), Rabbit Monoclonal (RM418) - 深圳欣博盛生物科技有限公司

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anti-CD25 (human), Rabbit Monoclonal (RM418)

品牌： Adipogen

产品货号： REV-31-1304-00-R100

规格： 100 µl

报价：

折后价：

数量： - +

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产品名称:

anti-CD25 (human), Rabbit Monoclonal (RM418)
别名:

IL-2Ralpha
产品描述:

CD25 (IL2 receptor alpha chain; IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors and oligodendrocytes. Though IL2RA has been used as a marker to identify CD4+FoxP3+ regulatory T cells in mice, it has been found that a large proportion of resting memory T cells constitutively express IL2RA in humans. IL2 plays an important role as a growth factor, differentiation factor and regulator of cell death. IL-2 stimulates the proliferation of B cells, augments natural killer cell activity and inhibits granulocyte macrophage colony formation. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, mastocytosis and tumor infiltrating lymphocytes. It functions as the receptor for HTLV-1 and is consequently expressed on neoplastic cells in adult T cell lymphoma/leukemia.
反应种属:
宿主来源:

Rabbit
实验应用:

IHC
靶标/特异性:
同种型:

Rabbit IgG
推荐稀释度:
免疫原:

A peptide corresponding to the N-terminus of human CD25.
免疫原种属:
克隆性:
克隆号:

RM418
纯化方式:
偶联:
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保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:
产品形式:

liquid
存储溶液:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
有效期:

Stable for at least 1 year after receipt when stored at -20°C.
产地:

瑞士
外观:
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URL:
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样本类型:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产品特点:
纯度:

Protein A purified.
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