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anti-HSP70 (human), Rabbit Monoclonal (RM432)
品牌: Adipogen
产品货号: REV-31-1320-00-R100
规格: 100 µl

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    anti-HSP70 (human), Rabbit Monoclonal (RM432)
  • 别名:
  • 产品描述:
    HSP70 is a molecular chaperone expressed constitutively under normal conditions to maintain protein homeostasis and is induced upon environmental stress. It functions by acting as molecular chaperones, facilitating protein refolding and preventing protein aggregation. It has been reported that extracellular HSP70 also exhibits immunomodulatory effects on innate and acquired immunity. HSP70 is membrane associated in lysosomes, mitochondria,and the outer surface of cancer cells. It plays a role in vesicle formation and protein trafficking. HSP70 expression in colorectal carcinoma and breast carcinoma has been significantly correlated with low differentiation and poor prognosis, whereas in renal cell carcinoma it has been reported to be associated with good prognosis. Expression of HSPs on the surface of tumor cells, instead of their normal intracellular location, suggests they play a role in inducing an immune response against cancer.
  • 反应种属:
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC, WB
  • 靶标/特异性:
  • 同种型:
    Rabbit IgG
  • 推荐稀释度:
  • 免疫原:
    A recombinant human HSP70 protein.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    RM432
  • 纯化方式:
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
  • 产品特点:
  • 纯度:
    Protein A purified.
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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