Fas antibody [LOB 3/17] (FITC)

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品牌： GeneTex

产品货号： GTX75107

规格： 100μg

报价：￥5600.00

折后价：￥5600.00

数量： - +

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产品名称:

Fas antibody [LOB 3/17] (FITC)
别名:

Fas cell surface death receptor , ALPS1A , APO-1 , APT1 , CD95 , FAS1 , FASTM , TNFRSF6
产品描述:
反应种属:

Human, Rhesus Monkey
宿主来源:

Mouse
实验应用:

FACS
靶标/特异性:
同种型:

IgG1
推荐稀释度:
免疫原:

Fusion protein comprising extracellular domain of human Fas linked to human Fc.
免疫原种属:

Human
克隆性:

Monoclonal
克隆号:

LOB 3/17
纯化方式:

Protein A purified
偶联:

FITC
产品浓度:

0.1 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
阳性对照:
保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
运输温度:

4°C
细胞定位:
预期分子量:

38
产品形式:

Liquid
存储溶液:

PBS, 1% BSA, 0.09% Sodium azide.
有效期:
产地:

美国
外观:
生产商:
功能与背景:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011]
URL:
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检测方法:
样本类型:

PBS, 1% BSA, 0.09% Sodium azide.
产品特点:
纯度:
生物活性:
内毒素水平:
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PubChem CID: