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产品名称:
anti-IL-37 (human), pAb
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别名:
Interleukin-1 Family Member 7; IL-1F7; FIL1 zeta; IL-1X; Interleukin-1 Homolog 4; IL-1H4; Interleukin-1 zeta; IL-1 zeta; IL-1RP1; IL1F7; FIL1Z, IL1H4, IL1RP1
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产品描述:
IL-37 (IL-1F7; IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
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反应种属:
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宿主来源:
Rabbit
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实验应用:
ELISA, IHC, IP, WB
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靶标/特异性:
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同种型:
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推荐稀释度:
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免疫原:
Recombinant human IL-37.
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产品浓度:
1 mg/ml
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表达系统:
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阳性对照:
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保存温度:
-20°C
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运输温度:
BLUE ICE
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预期分子量:
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产品形式:
liquid
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存储溶液:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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有效期:
Stable for at least 6 months after receipt when stored at -20°C.
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产地:
瑞士
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样本类型:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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