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anti-GPx8 (human), pAb (IN103)
品牌： Adipogen
产品货号： AG-25B-0028-C100
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-GPx8 (human), pAb (IN103)
  • 别名:
    Probable Glutathione Peroxidase 8; GSHPx-8
  • 产品描述:
    GPxs are glutathione peroxidases involved in balancing the H2O2 homeostasis in signaling cascades. GPxs have been known to catalyze the reduction of H2O2 or organic hydroperoxides to water or the corresponding alcohols, respectively, typically using glutathione (GSH) as reductant. GPx8 (probable glutathione peroxidase 8) is a 209-aa, 24kDa protein with an N-terminal cytosolic tip, a predicted transmembrane segment and a catalytic domain located in the endoplasmic reticulum (ER) lumen. GPx8 is a CysGPxs with low glutathione peroxidase activity. A recent study identified GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. GPx8 cleavage by NS3-4A occurs at Cys11, removing the cytosolic tip of GPx8 and was observed in different experimental systems as well as in liver biopsies from patients with chronic hepatitis C.
  • 反应种属:
  • 宿主来源:
    Rabbit
  • 实验应用:
    ICC, WB
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
    Recombinant GPx8 (human) (aa 38-209) fused to a GST-tag.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
  • 纯化方式:
  • 偶联:
  • 产品浓度:
    1 mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
  • 产品特点:
  • 纯度:
  • 生物活性:
  • 内毒素水平:
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  • 分子式:
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  • PubChem CID:
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