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产品名称:
HIF1 alpha antibody
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别名:
hypoxia inducible factor 1 subunit alpha , HIF-1-alpha , HIF-1A , HIF-1alpha , HIF1 , HIF1-ALPHA , MOP1 , PASD8 , bHLHe78
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产品描述:
HIF1 alpha antibody recognizes HIF1 alpha (HIF1a) protein, which is a subunit of the heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1). HIF-1 is a master regulator of homeostatic adaption to hypoxia (low oxygen supply) in various physiological and pathological conditions including normal development and cancer.
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反应种属:
Bovine, Human, Mouse, Rabbit, Rat
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宿主来源:
Rabbit
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实验应用:
ChIP assay, ICC/IF, IHC-Fr, IHC-P, IP, WB
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靶标/特异性:
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同种型:
IgG
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推荐稀释度:
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免疫原:
Recombinant protein encompassing a sequence within the C-terminus region of human HIF1 alpha. The exact sequence is proprietary.
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免疫原种属:
Human
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克隆性:
Polyclonal
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克隆号:
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纯化方式:
Purified by antigen-affinity chromatography.
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偶联:
Unconjugated
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产品浓度:
0.42 mg/ml (Please refer to the vial label for the specific concentration.)
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表达系统:
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阳性对照:
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保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
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运输温度:
4°C
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细胞定位:
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预期分子量:
93
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产品形式:
Liquid
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存储溶液:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
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有效期:
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产地:
美国
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外观:
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生产商:
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功能与背景:
Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
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样本类型:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
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