-
产品名称:
Tau antibody
-
别名:
microtubule associated protein tau , DDPAC , FTDP-17 , MAPTL , MSTD , MTBT1 , MTBT2 , PPND , PPP1R103 , TAU
-
产品描述:
Tau antibody detects Tau protein, a phosphorylated microtubule-associated protein with a predicted molecular weight of 79 kDa. Tau protein has six isoforms in humans generated from a single gene. Expression changes of these Tau isoforms are controlled during neuronal development and in various pathological conditions. Dysfunction of Tau is associated with neurodegenerative diseases including Alzheimer’s disease and frontotemporal dementia.
-
反应种属:
Human, Mouse, Rat
-
宿主来源:
Rabbit
-
实验应用:
ICC/IF, IHC, IHC-Fr, IHC-P, WB
-
靶标/特异性:
-
同种型:
IgG
-
推荐稀释度:
-
免疫原:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Tau. The exact sequence is proprietary.
-
免疫原种属:
Human
-
克隆性:
Polyclonal
-
克隆号:
-
纯化方式:
Purified by antigen-affinity chromatography.
-
偶联:
Unconjugated
-
产品浓度:
0.47 mg/ml (Please refer to the vial label for the specific concentration.)
-
表达系统:
-
阳性对照:
-
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
-
运输温度:
4°C
-
细胞定位:
-
预期分子量:
79
-
产品形式:
Liquid
-
存储溶液:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
-
有效期:
-
产地:
美国
-
外观:
-
生产商:
-
功能与背景:
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq]
-
URL:
-
灵敏度:
-
检测范围:
-
检测方法:
-
样本类型:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
-
产品特点:
-
纯度:
-
生物活性:
-
内毒素水平:
-
来源:
-
表达方式:
-
Accession #:
-
CAS号:
-
分子式:
-
溶解度:
-
PubChem CID: