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Recombinant Human IL-36alpha (IL-1F6)
品牌： PeproTech
产品货号： 200-36A-500ug
规格： 500ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Recombinant Human IL-36alpha (IL-1F6)
  • 别名:
    Interleukin-36alpha, IL36A, Interleukin-1 family member 6 (IL-1F6), FIL1ε (FIL1E), Interleukin-1ε (IL1E)
  • 产品描述:
    The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36alpha (IL-1F6), beta (IL-1F8), and gamma (IL-1F9). IL-36alpha is highly expressed in psoriatic plaques, as are IL-36beta and IL-36gamma, and is the only IL-1 family member found to be expressed by T cells, as well as monocytes and B cells. Primarily found in skin and lymphoid tissues, IL-36alpha is also found to a lesser extent in tissues of the fetal brain, trachea, stomach, and intestine. IL-36alpha signals through a combination of the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells, and the widely expressed IL-RAcP (IL-1 receptor accessory protein). IL-36alpha also functions as an agonist of NF-kappaB and MAPK pathways, and induces the production of proinflammatory cytokines and chemokines, including IL-6, IL-8, BD-2, and BD-3. Recombinant Human IL-36alpha is a 17.2 kDa protein containing 154 amino acid residues.
  • 反应种属:
  • 宿主来源:
    E.coli
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  • 推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
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  • 预期分子量:
    17.2 kDa
  • 产品形式:
    Bulk
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  • 产地:
    美国
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