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Recombinant Murine Adiponectin
品牌： PeproTech
产品货号： 315-26-250ug
规格： 250ug

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折后价：

数量： - +
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  • 产品名称:
    Recombinant Murine Adiponectin
  • 别名:
    Acrp-30, GBP-28, APM-1
  • 产品描述:
    Adiponectin is an adipose-derived secreted protein containing 236 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity. The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-alpha and class A scavenger receptor in macrophages). Recombinant Murine Adiponectin is a multimeric glycoprotein containing amino acids Val-21 to Asn-247 of the adiponectin precursor protein fused to an N-terminal histidine tag. As a result of glycosylation, Recombinant Murine Adiponectin migrates with an apparent molecular mass of approximately 31-36 kDa by SDS-PAGE gel, under reducing conditions.
  • 反应种属:
  • 宿主来源:
    Hi-5 Insect cells
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  • 推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
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  • 预期分子量:
    25.8 kDa
  • 产品形式:
    Bulk
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  • 产地:
    美国
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