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Recombinant Human GDF-15/MIC-1
品牌： PeproTech
产品货号： 120-28C-5ug
规格： 5ug

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折后价：

数量： - +
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  • 产品名称:
    Recombinant Human GDF-15/MIC-1
  • 别名:
    Growth/Differentiation Factor-15, MIC-1, Macrophage Inhibitory Cytokine 1, Placental TGFbeta, Prostate Differentiation Factor (PDF), PLAB, NRG-1
  • 产品描述:
    GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Recombinant Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 112 amino acid polypeptide chains. The calculated molecular weight of Recombinant Human GDF-15/MIC-1 is 24.6 kDa.
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  • 宿主来源:
    CHO cells
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  • 推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
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  • 预期分子量:
    24.6 kDa
  • 产品形式:
    Standard
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  • 产地:
    美国
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