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SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged)
品牌： Cayman
产品货号： 30429
规格： 50 µg

报价：
折后价：

数量： - +
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  • 产品名称:
    SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged)
  • 别名:
    SARS-CoV-2 Surface Receptor Binding Domain|Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein Receptor Binding Domain
  • 产品描述:
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus, a member of the Betacoronavirus genus, and the causative agent of COVID-19.{53462,53459,53461,55257,55258} The SARS-CoV-2 spike glycoprotein, also known as the surface glycoprotein, is located on the outer envelope of the virion.{53462} It is composed of an S1 and S2 subunit divided by a furin S-cleavage site not found in other SARS-CoVs.{46767,49561} The S1 subunit contains the receptor-binding domain (RBD), which binds to the carboxypeptidase angiotensin-converting enzyme 2 (ACE2), and the S1 and S2 subunits are cleaved by the protease TMPRSS2 to facilitate viral fusion with the host cell membrane.{49542,49536,49558} In this way, ACE2 acts as the functional receptor for SARS-CoV-2. Cayman’s SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged) protein can be used as an antigen or for Western blot, ELISA, protein-protein interaction studies, and other in vitro binding and in vivo functional assays.
  • 反应种属:
  • 宿主来源:
    HEK293 cells
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  • 保存温度:
    -80
  • 运输温度:
    -80
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  • 产品形式:
    1 mg/ml in a solution of PBS, pH 7.2
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
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  • 纯度:
    ≥90% estimated by SDS-PAGE
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