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Ebola Virus VP24 (subtype Zaire, strain H. sapiens-wt/GIN/2014/Kissidougou-C15) (recombinant)
品牌： Cayman
产品货号： 41067
规格： 100 µg

报价：
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数量： - +
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  • 产品名称:
    Ebola Virus VP24 (subtype Zaire, strain H. sapiens-wt/GIN/2014/Kissidougou-C15) (recombinant)
  • 别名:
    EBOV Viral Protein 24|EBOV Virion Protein 24
  • 产品描述:
    Ebola virus (EBOV) is an enveloped and negative-stranded RNA virus, a member of the Ebolavirus genus, and the causative agent of Ebola virus disease (EVD), a condition characterized by a hemorrhagic fever and a high mortality rate, that is endemic to western and equatorial Africa.{69796} The single-stranded RNA genome of EBOV encodes seven proteins: nucleoprotein (NP), virion protein 40 (VP40), VP35, VP30, VP24, glycoprotein (GP), and an RNA-dependent RNA polymerase (L).{69796,69797} EBOV VP24 is a monomeric structural protein that is composed of N- and C-terminal domains that form a pyramidal structure.{51796} It functions with VP35 and NP in nucleocapsid formation, and both N- and C-terminal domains of VP40 are required for proper nucleocapsid structure.{51798,69796} EBOV VP24 disrupts the innate immune viral response by inhibiting expression of the gene encoding IFN-λ1 and prevents phosphorylated STAT1 nuclear translocation and transcriptional activity in mammalian cells expressing VP40.{69796,51797,51796} Cayman's Ebola Virus VP24 (subtype Zaire, strain H. sapiens-wt/GIN/2014/Kissidougou-C15) (recombinant) protein consists of 233 amino acids and has a calculated molecular weight of 28.5 kDa.
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    -80
  • 运输温度:
    -80
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  • 产品形式:
    Lyophilized from sterile 50 mM Tris, with 500 mM sodium chloride
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  • 有效期:
    365
  • 产地:
    美国
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    ≥95% estimated by SDS-PAGE
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