INHBE (human, recombinant) - 深圳欣博盛生物科技有限公司

您现在的位置：首页 > 产品目录 > 产品分类 > 蛋白质，酶与肽 > 重组蛋白 > 其他重组蛋白

INHBE (human, recombinant)

品牌： Cayman

产品货号： 38059

规格： 100 µg

报价：

折后价：

数量： - +

问题咨询

官网链接

说明书

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

INHBE (human, recombinant)
别名:

Activin β-E Chain|Inhibin Subunit β E|Inhibin β-E Chain
产品描述:

Inhibin beta E chain (INHBE) is a member of the TGF-β superfamily.{67279} INHBE encodes a 350-amino acid pre-protein, which is proteolytically cleaved at Thr237 to release the mature INHBE peptide, and is a secreted protein mainly expressed in the liver. It exists as a homodimer, also known as activin E, or forms heterodimers with other inhibin beta chains such as INHBC.{67280} INHBE is a hepatokine that is involved in hepatocyte viability, thermogenesis, and insulin sensitivity and binds to follistatin (Item No. 31839).{67280,67281,67279} Overexpression of INHBE induces apoptosis in hepatocytes and INHBE-containing conditioned medium induces expression of genes involved in adipocyte differentiation, which can be blocked by the activin receptor-like kinase (ALK) inhibitor SB-431542 (Item No. 13031).{67280,67281} Hepatic expression of human INHBE decreases plasma glucose levels and increases body temperature in mice.{67281} Loss-of-function mutations in INHBE are associated with favorable body fat distribution and a decreased risk of developing type 2 diabetes.{67282} Increased tumor levels of INHBE positively correlate with increasing tumor grade and negatively correlate with poor overall survival in patients with clear-cell renal cell carcinoma (ccRCC).{67283} Cayman’s INHBE (human, recombinant) protein is a disulfide-linked homodimer. The reduced monomer, composed of INHBE (amino acids 237-350) fused to human IgG1 Fc at its N-terminus, consists of 374 amino acids and has a calculated molecular weight of 40.9 kDa.
反应种属:
宿主来源:
实验应用:
靶标/特异性:
同种型:
推荐稀释度:
免疫原:
免疫原种属:
克隆性:
克隆号:
纯化方式:
偶联:
产品浓度:
表达系统:
阳性对照:
保存温度:

-80
运输温度:

-80
细胞定位:
预期分子量:
产品形式:

Lyophilized from sterile PBS, pH 7.4, with 5% trehalose, 5% mannitol, and 0.01% Tween 80
存储溶液:
有效期:

365
产地:

美国
外观:
生产商:
功能与背景:
URL:
灵敏度:
检测范围:
检测方法:
样本类型:
产品特点:
纯度:

≥90% as determined by SDS-PAGE
生物活性:
内毒素水平:
来源:
表达方式:
Accession #:
CAS号:
分子式:
溶解度:
PubChem CID: