您好，欢迎光临欣博盛生物科技商城！
服务热线：400 680 0892
购物车图片 购物车 ( )
sFRP1 (human, recombinant)
品牌： Cayman
产品货号： 38061
规格： 50 µg

报价：
折后价：

数量： - +
问题咨询
官网链接
说明书
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
  • 产品名称:
    sFRP1 (human, recombinant)
  • 别名:
    SARP-2|Secreted Apoptosis-related Protein 2|Secreted Frizzled-related Protein 1
  • 产品描述:
    Secreted frizzled-related protein 1 (sFRP1) is a Wnt inhibitor and a member of the sFRP family.{66323,66324} It is composed of a signal peptide, a cysteine-rich domain, and a netrin-like domain.{66323} sFRP1 is ubiquitously expressed, with the highest levels in the heart, ovary, testis, and small intestine.{66325} It inhibits Wnt signaling by sequestering Wnt directly via the cysteine-rich or netrin-like domains or competing with Wnt for binding to the cysteine-rich domain of Frizzled (Fz) receptors.{66323} sFRP1 is involved in apoptosis, adipocyte differentiation, angiogenesis, osteoblast proliferation and differentiation, development, and hematopoietic stem cell maintenance.{66323,66324} Myocardial overexpression of Sfrp1 protects against decreases in cardiac function and increases in myocardium apoptosis in a mouse model of heart failure induced by transverse aortic constriction.{66326} Tumor protein levels of sFRP1 are decreased in early-stage breast cancer, which is associated with poor prognosis.{66327} Cayman’s sFRP1 (human, recombinant) protein can be used for cell-based assays. This protein consists of 294 amino acids, has a calculated molecular weight of 34 kDa, and a predicted N-terminus of Ser32 after signal peptide cleavage. By SDS-PAGE, under reducing conditions, the apparent molecular mass of the protein is 38 kDa due to glycosylation.
  • 反应种属:
  • 宿主来源:
  • 实验应用:
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
  • 纯化方式:
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -80
  • 运输温度:
    -80
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    Lyophilized from sterile PBS, pH 7.4
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
  • 产品特点:
  • 纯度:
    ≥97% as determined by SDS-PAGE
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
关注欣博盛公众号
Copyright ©2021 - 2023 深圳欣博盛生物科技有限公司
粤ICP备08007346号
  网站地图
犀牛云提供企业云服务