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VSTM5 (human):Fc (human) (rec.) (non-lytic)
品牌： Adipogen
产品货号： AG-40B-0237-C050
规格： 50 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    VSTM5 (human):Fc (human) (rec.) (non-lytic)
  • 别名:
    V-set and Transmembrane Domain-containing Protein 5; C11orf90
  • 产品描述:
    The V-set and transmembrane domain-containing protein (VSTM) family is composed of 8 proteins: VSTM1v1, VSTM1v2, VSTM2a, VSTM2b, VSTM2L, VSTM3, VSTM4 and VSTM 5. Members of the VSTM family are associated with the regulation of functions of immune cells, adipose cells and neuronal cells. The VSTM family is an immunoglobulin (Ig) superfamily that shares structural similarities with the B7-like transmembrane proteins involved in immune regulation. VSTM1 and VSTM4 play positive and negative roles in macrophage activation, respectively. VSTM3 (TIGIT) acts as a co-inhibitory receptor that suppresses the cytokine production of T cells and NK cells. V-set and transmembrane domain-containing protein 5 (Vstm5), a newly characterized small membrane glycoprotein highly expressed in the CNS, facilitates the formation of neuronal dendrites and protrusions such as dendritic filopodia. Regulatory roles of VSTM5 for in vitro and in vivo immune responses have been reported. VSTM5 functions as a novel immune checkpoint by regulating T cell proliferation and cytokine production, Treg generation by maintenance of T cell energy and possibly induction of T cell apoptosis.
  • 反应种属:
  • 宿主来源:
    HEK 293 cells
  • 实验应用:
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  • 免疫原:
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  • 产品浓度:
    1mg/ml after reconstitution.
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~55kDa (SDS-PAGE)
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized. Contains PBS.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C.Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
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  • 样本类型:
    Lyophilized. Contains PBS.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
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