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Recombinant Human sIL-15 Receptor alpha Fc
品牌: PeproTech
产品货号: 200-15RA-20ug
规格: 20ug

报价:
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数量: - +
产品详情
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  • 产品名称:
    Recombinant Human sIL-15 Receptor alpha Fc
  • 别名:
    soluble Interleukin‐15 receptor subunit alpha, soluble IL‐15RA, CD215
  • 产品描述:
    IL‐15 signaling is an important factor in proliferating, activating, and immunomodulating primarily T cells. IL‐15R alpha is an IL‐15 specific, single pass membrane receptor which complexes with IL‐2R beta and IL‐2R gamma to form a high affinity IL‐15 receptor. Additionally, the IL‐15/IL‐15R complex is capable of binding to IL‐2 beta/gamma receptors on other cells, therefore enabling IL‐15 to indirectly activate cells expressing IL‐2 beta/gamma receptors. A soluble form of IL‐15 receptor alpha is naturally produced by proteolytic cleavage of the membrane‐bound precursor. This naturally occurring soluble form can act as a modulator of IL‐15 signaling through the inhibition of IL‐15 receptor binding. Recombinant Human sIL‐15 Receptor alpha Fc has a calculated molecular weight of 44.4 kDa protein and contains 408 amino acid residues, which consists of the extracellular domain of IL‐15R alpha fused to the Fc portion of human IgG. Due to glycosylation, it migrates at an apparent molecular weight of 50‐60 kDa, under reducing conditions.
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  • 宿主来源:
    Hi-5 Insect cells
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  • 推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
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  • 预期分子量:
    44.4 kDa
  • 产品形式:
    Standard
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  • 产地:
    美国
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