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Fc (LALA-PG)-KIH (human) IgG1 Control (rec.)
品牌： Adipogen
产品货号： AG-35B-0018-C050
规格： 50 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Fc (LALA-PG)-KIH (human) IgG1 Control (rec.)
  • 别名:
    Fc (LALA-PG) Knobs-into-Holes (human) IgG1; Immunoglobulin 1 Fragment Constant
  • 产品描述:
    Negative control in experiments with recombinant proteins fused to human IgG1 Fc (LALA-PG)-KIH (Knobs-into-Holes) (e.g. Prod. No. AG-40B-0248). This protein is not an appropriate negative control for other standard Fc protein constructs. The protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.) is produced by using two different vectors, one encoding for the Fc (LALA-PG) Knobs sequence with a small linker (synthesizing a protein of 29kDa) and one encoding for the Fc (LALA-PG) Holes sequence (synthesizing a protein of 28kDa). Both vectors transfected into HEK293 cells produce both Fc molecules (Knobs-into-Holes technology; J.B. Ridgway, et al.; Protein Eng. 9, 617 (1996)) required for dimerization and for secretion of the final protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.). The Fc contains the mutations LALA-PG that abolish the interaction between the Fc and FcgammaRs and therefore Fc undesirable effects.
  • 反应种属:
  • 宿主来源:
    HEK 293 cells
  • 实验应用:
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  • 推荐稀释度:
  • 免疫原:
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  • 产品浓度:
    After reconstitution: 1mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~28kDa (SDS-PAGE)
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized. Contains PBS.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C.Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 样本类型:
    Lyophilized. Contains PBS.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
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