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产品名称:
FABP1 (rat recombinant)
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别名:
Fatty Acid Binding Protein 1|L-FABP|Liver-FABP|Liver-Fatty Acid Binding Protein
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产品描述:
Fatty acid binding protein 1 (FABP1) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids.{11979} FABP1 is composed of ten antiparallel β strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acids. Expression of FABP1 is decreased in hepatoblastoma and hepatocellular carcinoma making the protein a potential tumor marker. Moreover, studies have suggested FABP1 as a potential biomarker for both liver and kidney injury.{11979} Cayman’s FABP1 has been functionally characterized by a fluorescence displacement assay using the fluorescent fatty acid analogue 11-(dansyl amino)undecanoic acid (DAUDA). Both arachidonic acid and oleic acid effectively displace DAUDA from the FABP binding pocket in a concentration-dependent manner.
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保存温度:
-80
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运输温度:
-80
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产品形式:
A solution in 50 mM of sodium phosphate, pH 7.2, with 20% glycerol and 150 mM sodium chloride
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有效期:
365
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产地:
美国
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纯度:
≥90%
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