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ISG15 (human) (rec.) (Rhodamine 110)
品牌: Adipogen
产品货号: SBB-PS0002-C050
规格: 50 ug

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    ISG15 (human) (rec.) (Rhodamine 110)
  • 别名:
    ISG15 Ubiquitin-like Modifier; G1P2; IFI15; IP17; UCRP
  • 产品描述:
    ISG15 (Interferon Stimulated Gene, 15kDa) is a ubiquitin-like modifier which initiates innate immune response by activating RIG-I signaling, stimulating NK-cell proliferation, inhibiting viral budding and acting as an IFNgamma-inducing cytokine. ISG15 contains two tandem ubiquitin homology domains and is cross-reactive with alpha-Ubiquitin antibodies. Conjugation of ISG15 to a substrate protein occurs through a ubiquitin like cascade via an E1 (UBE1L), E2 (UbcH8/UBE2L6) and E3 (not yet discovered.) Deconjugation normally occurs via UBP43 (USP18), however there are several viral proteases that are able to hydrolyze ISG15 conjugates in order to evade immune response. These include the OTU-containing protease of Crimean-Congo Hemorrhagic Fever nairovirus and the Papain-Like Protease (PLPro) of the SARS coronavirus.
  • 反应种属:
  • 宿主来源:
    E. coli
  • 实验应用:
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  • 纯化方式:
  • 偶联:
    Rhodamine
  • 产品浓度:
    Lot dependent.
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -80°C
  • 运输温度:
    Dry Ice
  • 细胞定位:
  • 预期分子量:
    ~18kDa
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In 50mM MES pH 6.0, 100mM sodium chloride, 10% glycerol.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -80°C.
  • 产地:
    瑞士
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  • 样本类型:
    Liquid. In 50mM MES pH 6.0, 100mM sodium chloride, 10% glycerol.
  • 产品特点:
  • 纯度:
    >97% (LCMS)
  • 生物活性:
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