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Ubiquitin aldehyde (human) (rec.)
品牌: Adipogen
产品货号: SBB-PS0031-C050
规格: 50 ug

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    Ubiquitin aldehyde (human) (rec.)
  • 别名:
  • 产品描述:
    Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of eukaryotic organisms. The addition of ubiquitin to a substrate protein is called ubiquitination or ubiquitylation. Ubiquitination can affect proteins in many ways: it can signal for their degradation via the proteasome, alter their cellular location, affect their activity and promote or prevent protein interactions. Removal of ubiquitin from a substrate protein occurs via deconjugating enzymes, of which there are nearly 100 known enzymes with various linkage specificities. This product consists of a full-length human, mature ubiquitin polypeptide (amino acids 1-76), expressed in E.coli with a C-terminal warhead (Aldehyde). Ubiquitin aldehyde is a potent, irreversible and specific inhibitor of deubiquitinating enzymes (DUBs) based on a C-terminal electrophilic aldehyde group. Ubiquitin aldehyde can be used for activity profiling experiments and determining DUB inhibitor specificity. It targets four of the five major DUB families: UCH (Ubiquitin C-terminal hydrolases), USP (Ubiquitin specific proteases), OTU (Ovarian tumor proteases) and MJD (Machado-Josephin domain proteases) while JAMM metalloproteases are not inhibited.
  • 反应种属:
  • 宿主来源:
    E. coli
  • 实验应用:
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  • 产品浓度:
    Lot dependent.
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -80°C
  • 运输温度:
    Dry Ice
  • 细胞定位:
  • 预期分子量:
    ~9kDa
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In 50mM NaOAc pH 5.0.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -80°C.
  • 产地:
    瑞士
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  • 样本类型:
    Liquid. In 50mM NaOAc pH 5.0.
  • 产品特点:
  • 纯度:
    >97% (LCMS)
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