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产品名称:
AHA1 Protein
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别名:
Aha1 Protein, SHSA1 Protein, HSPC322 Protein, p38 Protein
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产品描述:
Human Recombinant AHA1 Protein
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反应种属:
Human
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宿主来源:
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实验应用:
WB | SDS-PAGE | Functional Assay
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靶标/特异性:
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同种型:
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推荐稀释度:
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免疫原:
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免疫原种属:
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克隆性:
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克隆号:
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纯化方式:
Multi-Step Purified
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偶联:
No tag
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产品浓度:
Lot/batch specific. See included datasheet.
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表达系统:
E. coli
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阳性对照:
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保存温度:
-20ºC
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运输温度:
Blue Ice or 4ºC
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细胞定位:
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预期分子量:
~38 kDa
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产品形式:
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存储溶液:
20mM HEPES buffer pH7.2, 80mM NaCl, 10% glycerol
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有效期:
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产地:
加拿大
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外观:
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生产商:
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功能与背景:
Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).
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URL:
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灵敏度:
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检测范围:
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检测方法:
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样本类型:
20mM HEPES buffer pH7.2, 80mM NaCl, 10% glycerol
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产品特点:
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纯度:
>90%
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生物活性:
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内毒素水平:
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来源:
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表达方式:
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Accession #:
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CAS号:
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分子式:
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溶解度:
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PubChem CID: