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产品名称:
HOP Protein
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别名:
HSP co chaperone Protein
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产品描述:
Human Recombinant HOP Protein
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反应种属:
Human
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宿主来源:
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实验应用:
WB | SDS-PAGE | Functional Assay
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靶标/特异性:
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同种型:
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推荐稀释度:
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免疫原:
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免疫原种属:
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克隆性:
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克隆号:
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纯化方式:
Affinity Purified
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偶联:
His tag
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产品浓度:
Lot/batch specific. See included datasheet.
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表达系统:
E. coli
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阳性对照:
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保存温度:
-20ºC
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运输温度:
Blue Ice or 4ºC
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细胞定位:
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预期分子量:
~63 kDa
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产品形式:
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存储溶液:
25mM HEPES pH 7.2, 50mM NaCl, 1mM DTT, 10% glycerol
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有效期:
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产地:
加拿大
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外观:
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生产商:
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功能与背景:
Hop (HSP70/HSP90 Organizing Protein), or Stress-induced Phosphoprotein 1 (STI1) as it is also known, is a 60kDa protein that belongs to the large group of co-chaperones which regulate and assist the major chaperones. It is located in diverse cellular regions and can move between the cytoplasm and the nucleus. It functions to reversibly link together the protein chaperones HSP70 and HSP90. HOP contains three tetratricopeptide repeat (TPR) domains, TPR1, TPR2a and TPR2b. HSP70 binding has been localized to TRP1 and sp90 binding have been localized to TPR2a (1). It has also been found to modulate the chaperone activities of the linked proteins and possible interacts with other chaperones and proteins. It has also been found to participate in other complexes besides the HSP70/HSP90 one (2). HOP is closely related to human 63kDa protein that is sensitive to simian virus SV40 transformation, and is related to the yeast heat-shock- responsive STI1 gene product (3, 4).
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URL:
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灵敏度:
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检测范围:
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检测方法:
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样本类型:
25mM HEPES pH 7.2, 50mM NaCl, 1mM DTT, 10% glycerol
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产品特点:
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纯度:
>90%
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生物活性:
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内毒素水平:
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来源:
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表达方式:
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Accession #:
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CAS号:
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分子式:
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溶解度:
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PubChem CID: