Alpha Synuclein A53T Mutant Monomers (Type 1) - 深圳欣博盛生物科技有限公司

您现在的位置：首页 > 产品目录 > 产品分类 > 蛋白质，酶与肽 > 重组蛋白 > 其他重组蛋白

Alpha Synuclein A53T Mutant Monomers (Type 1)

品牌： Stressmarq

产品货号： SPR-325E

规格： 100 µg x5

报价：

折后价：

数量： - +

问题咨询

官网链接

说明书

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Alpha Synuclein A53T Mutant Monomers (Type 1)
别名:

A53T mutant alpha synuclein, A53T mutated SNCA, A53T Alpha synuclein monomer, Ala53thr mutant alpha synuclein, Alpha synuclein protein, Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, Alpha synuclein monomers, SYN protein, Parkinson disease familial 1 Protein
产品描述:

Human Recombinant A53T Mutant Alpha Synuclein Protein Monomers (Type 1)
反应种属:

Human
宿主来源:
实验应用:

WB | SDS-PAGE | In vivo assay | In vitro assay
靶标/特异性:
同种型:
推荐稀释度:
免疫原:
免疫原种属:
克隆性:
克隆号:
纯化方式:

Ion-exchange Purified
偶联:

No tag
产品浓度:

2 mg/ml
表达系统:

E. coli
阳性对照:
保存温度:

-80ºC
运输温度:

Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
细胞定位:
预期分子量:

~14.46 kDa
产品形式:
存储溶液:

PBS pH 7.4
有效期:
产地:

加拿大
外观:
生产商:
功能与背景:

Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson's disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6). The A53T mutation is a missense point mutation where alanine is replaced by threonine at the 53rd amino acid. This mutation has been linked to early-onset Parkinson's Disease and increased rates of alpha synuclein fibrillization.
URL:
灵敏度:
检测范围:
检测方法:
样本类型:

PBS pH 7.4
产品特点:
纯度:

>95%
生物活性:
内毒素水平:
来源:
表达方式:
Accession #:
CAS号:
分子式:
溶解度:
PubChem CID: