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Transthyretin Y78F Variant Monomers
品牌： Stressmarq
产品货号： SPR-452C
规格： 100 µg x2

报价：
折后价：

数量： - +
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  • 产品名称:
    Transthyretin Y78F Variant Monomers
  • 别名:
    Amyloid polyneuropathy Protein Monomer, Amyloidosis I Protein Monomer, ATTR Protein Monomer, Carpal tunnel syndrome 1 Protein Monomer, CTS Protein Monomer, CTS1 Protein Monomer,= HEL111 Protein Monomer, HsT2651 Protein Monomer, PALB Protein Monomer, Prealbumin Protein Monomer, Prealbumin amyloidosis type I Protein Monomer, Prealbumin Thyroxine-binding Protein Monomer, TBPA Protein Monomer, Thyroxine binding prealbumin Protein Monomer, Transthyretin Protein Monomer, TTHY_HUMAN Protein Monomer,TTR Protein Monomer, TTR protein
  • 产品描述:
    Human Recombinant Transthyretin Y78F Variant Protein Monomers
  • 反应种属:
    Human
  • 宿主来源:
  • 实验应用:
    WB | SDS-PAGE | In vivo assay | In vitro assay
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
  • 纯化方式:
    Ion-exchange Purified
  • 偶联:
    No tag
  • 产品浓度:
    Lot/batch specific. See included datasheet.
  • 表达系统:
    E. coli
  • 阳性对照:
  • 保存温度:
    -80ºC
  • 运输温度:
    Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
  • 细胞定位:
  • 预期分子量:
    15.887 kDa
  • 产品形式:
  • 存储溶液:
    PBS pH 7.4
  • 有效期:
  • 产地:
    加拿大
  • 外观:
  • 生产商:
  • 功能与背景:
    Transthyretin is a transport protein in the serum and cerebospinal fluid that carried the thyroid hormone Thyroxine and retinol-binding protein bound to retinol. TTR misfolding and aggregation is known to be associated with the amyloiddiseases SSA, FAP and FAC (1-5). TTR is also thought to have beneficial side effects, such as binding to beta-amyloid protein, preventing beta-amyloid from accumulating into the plaques associated with Alzheimer's Disease (6). The mutant variant Y78F indicates a destabilization of the contacts between the alpha-helix and AB loop and the body of the molecule, potentially leading to applications in immne therapy for FAP (7).
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    PBS pH 7.4
  • 产品特点:
  • 纯度:
    >95%
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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