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Tau (K18) Delta K280 Mutant Monomers
品牌： Stressmarq
产品货号： SPR-476E
规格： 100 µg x5

报价：
折后价：

数量： - +
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  • 产品名称:
    Tau (K18) Delta K280 Mutant Monomers
  • 别名:
    Tau monomer, Tau protein monomer, Tau protein, microtubule-associated protein Tau, MAPT, MAP, microtubule-associated protein, Truncated Tau Protein Monomer, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 2, tubulin-associated unit, 95-amino acid Tau protein fragment, Truncated Tau Protein, MAPT DeltaK280, ΔK280 Tau, K18 delta K280 Tau, truncated ΔK280 Tau
  • 产品描述:
    Human Recombinant Tau (K18) Delta K280 Mutant Protein Monomers
  • 反应种属:
    Human
  • 宿主来源:
  • 实验应用:
    WB | SDS-PAGE | In vivo assay | In vitro assay
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
  • 纯化方式:
    Ion-exchange Purified
  • 偶联:
    No Tag
  • 产品浓度:
    2 mg/ml
  • 表达系统:
    E. coli
  • 阳性对照:
  • 保存温度:
    -80ºC
  • 运输温度:
    Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
  • 细胞定位:
  • 预期分子量:
    ~15 kDa
  • 产品形式:
  • 存储溶液:
    PBS pH 7.4
  • 有效期:
  • 产地:
    加拿大
  • 外观:
  • 生产商:
  • 功能与背景:
    Alzheimer’s Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). The ΔK280 mutation is associated with frontotemporal dementia and promotes fibrillization into paired helical filaments (PHFs) in the absence of heparin and other inducers (4). K18 is a truncated form of human tau containing only the 4 microtubule binding repeats (5).
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    PBS pH 7.4
  • 产品特点:
  • 纯度:
    >95%
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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