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Protein Phosphatase 2A C subunit (L309 deletion mutant; human, recombinant)
品牌: Cayman
产品货号: 10011237
规格: 10 µg

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    Protein Phosphatase 2A C subunit (L309 deletion mutant; human, recombinant)
  • 别名:
    PP2A Cα|PP2A L309|PP2A Δ309
  • 产品描述:
    Reversible protein phosphorylation is a fundamental regulatory mechanism in all aspects of biology. Protein phosphatase 2A (PP2A) is a divalent cation-independent protein serine/threonine phosphatase involved in regulating numerous cellular processes including the cell cycle, growth and differentiation and is also thought to be a potential tumor suppressor.{15392} PP2A is a hetrotrimeric protein containing a 65 kDa scaffolding A subunit, a regulatory B subunit and a 36 kDa catalytic C subunit.{15393} The recombinant PP2A catalytic subunit has the characteristic properties of Type 2A phosphatases and is highly sensitive to okadaic acid and microcystins.{15391} The provided preparation of the catalytic subunit of PP2A is useful for the study of enzyme kinetics and regulation, to dephosphorylate target substrates and to evaluate the effects of test substances on the activity of the phosphatase.
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  • 保存温度:
    -80
  • 运输温度:
    -80
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  • 产品形式:
    20 mM Tris, pH 7.5, with 100 mM sodium chloride, 5 mM MgCl2, 1 mM EDTA, and 25% glycerol
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  • 有效期:
    365
  • 产地:
    美国
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