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Soluble Epoxide Hydrolase (mouse, recombinant)
品牌： Cayman
产品货号： 10011670
规格： 50 µg

报价：
折后价：

数量： - +
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  • 产品名称:
    Soluble Epoxide Hydrolase (mouse, recombinant)
  • 别名:
    Cytosolic Epoxide Hydrolase (CEH)|EPHX2|Epoxide Hydrolase 2|sEH
  • 产品描述:
    Soluble epoxide hydrolase (sEH) is a member of the α/β-hydrolase fold enzyme family that catalyzes the hydrolysis of bioactive fatty acid epoxides to inactive vicinal diols.{52737} It is a homodimer in which each subunit is composed of two domains, a C-terminal epoxide hydrolase domain and an N-terminal phosphatase domain.{52738,15765} sEH is localized to the cytoplasm or to peroxisomes in a tissue-specific manner and is found in various tissues, including skin, lung, uterus, kidney, brain, and myocardium.{52740,52739} sEH is also expressed in the vasculature and inhibition of sEH attenuates pathogenic vascular remodeling and hypertension via preservation of cardioprotective epoxyeicosatrienoic acids (EETs) in rat models of atherosclerosis and hypertension, respectively.{52741} Inhibition of sEH also has a protective role in various diseases, including inflammatory bowel disease, osteoarthritis, seizure, stroke, and Alzheimer’s disease, as well as in various chronic pain states.{52737,50771} Cayman’s Soluble Epoxide Hydrolase (mouse, recombinant) protein can be used for enzyme activity assays.
  • 反应种属:
  • 宿主来源:
    Insect cells
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  • 阳性对照:
  • 保存温度:
    -80
  • 运输温度:
    -80
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  • 产品形式:
    TBS buffer at pH 7.4 with 20% glycerol
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
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  • 纯度:
    ≥95% estimated by SDS-PAGE
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