您好，欢迎光临欣博盛生物科技商城！
服务热线：400 680 0892
购物车图片 购物车 ( )
PAD3 (human, recombinant)
品牌： Cayman
产品货号： 10786
规格： 100 µg

报价：
折后价：

数量： - +
问题咨询
官网链接
说明书
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
  • 产品名称:
    PAD3 (human, recombinant)
  • 别名:
    PADI3|PDI3|Peptidylarginine Deiminase 3|Protein Arginine Deiminase 3
  • 产品描述:
    Protein arginine deiminase 3 (PAD3) catalyzes the conversion of arginine residues to citrulline within its cellular protein substrates, which include S100A3, trichohyalin, and filaggrin, resulting in the loss of a positive charge, which can alter protein structure and/or function.{45610} It exists as a homodimer and is composed of a C-terminal catalytic domain and an N-terminal domain that contains two immunoglobulin G (IgG) subdomains.{60813} PAD3 is primarily expressed by differentiated keratinocytes in the epidermis and hair follicles where it has roles in the shaping and mechanical strengthening of hair.{60813,36391} It is also expressed by neural stem cells where it modulates cell death by regulating the nuclear translocation of apoptosis-inducing factor (AIF), in mammary glands where it citrullinates proteins during lactation, and cancer cells where it promotes cancer cell invasion.{60814,34764,60815} Mutations in PADI3 are associated with uncombable hair syndrome. Cayman's PAD3 (human, recombinant) protein can be used for enzyme activity assays.
  • 反应种属:
  • 宿主来源:
  • 实验应用:
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
  • 纯化方式:
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -80
  • 运输温度:
    -80
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    50 mM HEPES, pH 8.0, containing 300 mM sodium chloride, 1 mM DTT, and 10% glycerol
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
  • 产品特点:
  • 纯度:
    ≥85% estimated by SDS-PAGE
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
关注欣博盛公众号
Copyright ©2021 - 2023 深圳欣博盛生物科技有限公司
粤ICP备08007346号
  网站地图
犀牛云提供企业云服务