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PDE9A2 (human, recombinant)
品牌： Cayman
产品货号： 32039
规格： 100 µg

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折后价：

数量： - +
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  • 产品名称:
    PDE9A2 (human, recombinant)
  • 别名:
    High Affinity cGMP-specific 3',5'-cyclic Phosphodiesterase 9A
  • 产品描述:
    Phosphodiesterase 9A (PDE9A) is a high-affinity cGMP-specific cyclic nucleotide phosphodiesterase.{53752} Alternative splicing in the 5' region of PDE9A mRNA results in a variety of PDE9A isoforms, including PDE9A2, whereas the 3' region encoding the catalytic PDE domain does not vary between isoforms.{53750,53753} PDE9A2 mRNA is expressed in colon, prostate, spleen, peripheral blood leukocytes, small intestine, thymus, testis, and ovary.{53750} PDE9A2 localizes to membrane ruffles, the perinuclear region, and other membrane regions when transiently overexpressed in HeLa and COS-1 cells.{53753} PDE9A expression is elevated in reticulocytes and neutrophils isolated from patients with sickle cell disease compared with healthy individuals.{53751} Cayman's PDE9A2 (human, recombinant) protein consists of 770 amino acids and has a calculated molecular weight of 89.5 kDa. By SDS-PAGE, under reducing conditions, the apparent molecular mass of the protein is approximately 75 kDa.
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  • 保存温度:
    -80
  • 运输温度:
    -80
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  • 产品形式:
    Lyophilized from sterile 20 mM Tris, pH 7.4, with 500 mM sodium chloride, 5 mM GSH, and 10% glycerol
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
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  • 纯度:
    ≥90% estimated by SDS-PAGE
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