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Prostaglandin F2α Ethanolamide-d4
品牌： Cayman
产品货号： 316013-50 µg
规格： 50 µg

报价：
折后价：

数量： - +
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  • 产品名称:
    Prostaglandin F2α Ethanolamide-d4
  • 别名:
    Dinoprost Ethanolamide-d4|PGF2α-EA-d4
  • 产品描述:
    Prostaglandin F2α ethanolamide (PGF2α-EA-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGF2α-EA by GC- or LC-mass spectrometry. PGF2α-EA is produced by cyclooxygenase 2 (COX-2) metabolism of the endogenous cannabinoid arachidonoyl ethanolamide (AEA) found in brain, liver, and other mammalian tissues.{2415} AEA can be metabolized by fatty acid amide hydrolase (FAAH) to give free arachidonic acid, which is the well known and conventional substrate for COX enzymes. However, it has also been reported that AEA can be used directly by COX-2 to produce ethanolamide congeners of the classical prostaglandins, including PGE2.{5089} PGF2α-EA has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents.{8671}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    401.6
  • 产品形式:
    A solution in methyl acetate
  • 存储溶液:
  • 有效期:
    730
  • 产地:
    美国
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  • 纯度:
    ≥99% deuterated forms (d1-d4)
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  • 分子式:
    C22H35D4NO5
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