产品描述:
Cercosporin is a pigmented phytotoxin isolated from the fungus C. kikuchii that produces reactive oxygen species in plant hosts leading to cellular damage.{37038,37041} It exhibits light-activated cytotoxic effects in vitro with cytotoxic concentration (CC50) values of 241, 282, and 174 nM in HeLa, A432, and MCF-7 cells, respectively.{37040} It is a selective inhibitor of PKC (IC50 = 600-1,300 nM) with no activity on PKA or PPK at concentrations over 180 µM.{37039}