产品描述:
N-desethyl Sunitinib is an active metabolite of sunitinib (Item No. 13159), a small molecule, multi-targeted receptor tyrosine kinase inhibitor.{17043,40284} N-desethyl Sunitinib is formed when sunitinib undergoes N-de-ethylation by the cytochrome P450 (CYP) isomer CYP3A4.{40284} N-desethyl Sunitinib is pharmacologically active having similar inhibitory activity to sunitinib.