产品描述:
AG-528 is a tyrphostin that inhibits EGFR and HER2 (IC50s = 12 and 4.9 μM, respectively, for inhibition of autophosphorylation).{45071} It also inhibits pantothenate kinase 3 (PanK3; IC50 = 3 μM).{46757} AG-528 inhibits EGF-dependent proliferation of HER14 cells (IC50 = 25 μM).{45071}