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Adenosine Kinase Inhibitor (hydrate)
品牌： Cayman
产品货号： 17569-10 mg
规格： 10 mg

报价：
折后价：

数量： - +
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  • 产品名称:
    Adenosine Kinase Inhibitor (hydrate)
  • 别名:
    ABT-702
  • 产品描述:
    Adenosine provides homeostatic reductions in cell excitability during tissue stress and trauma by negatively modulating intercellular signaling. Adenosine kinase is the key metabolizing enzyme that regulates cellular adenosine concentrations. Inhibition of adenosine kinase represents a mechanism to selectively enhance the protective actions of adenosine during tissue trauma without producing the nonspecific effects associated with the systemic administration of adenosine receptor agonists. Adenosine kinase inhibitor is a non-nucleoside pyridopyrimidine compound that blocks the action of adenosine kinase in an adenosine-competitive and reversible manner (IC50 = 1.7 nM in cell-free assays).{28714} It is several orders of magnitude more selective for adenosine kinase over the adenosine A1, A2A, A3 receptors, the adenosine transporter, and adenosine deaminase.{28714} This compound has been shown to suppress nociception in various rodent pain models.{28714,28715}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    463.3
  • 产品形式:
    A crystalline solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • 分子式:
    C22H19BrN6O • XH2O
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