产品描述:
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.{45257,49486} It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 µM).{45257} (5E)-7-Oxozeaenol inhibits proliferation of MCF-7, H460, SF-268, HT-29, and MDA-MB-435 human cancer cells with IC50 values of 4.9, 1.2, 5.6, 4.4, and 5.5 µM, respectively.{49486}