产品描述:
THZ1-R is a non-cysteine reactive derivative of the cyclin-dependent kinase 7 (Cdk7) inhibitor THZ1 (Item No. 9002215).{31732} THZ1-R inhibits Cdk7 (IC50s = 142-241 nM) less potently than THZ1 and lacks antiproliferative activity against T cell acute lymphoblastic leukemia (T-ALL) cell lines.