产品描述:
Bisindolylmaleimide IV (BIM IV) is a cell permeable inhibitor of protein kinase C (PKC) with IC50 values reported to range from 0.10 to 0.55 µM.{17276,17275,17277,17278} BIM IV was designed to be more discriminative than its parent compound, the non-selective PKC inhibitor, staurosporine (Item No. 81590). However, BIM IV also inhibits protein kinase A with IC50 values ranging from 2 to 11.8 µM.{17276,17275}