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D-myo-Inositol-1,3,4-triphosphate (sodium salt)
品牌: Cayman
产品货号: 60972-500 µg
规格: 500 µg

报价:
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数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    D-myo-Inositol-1,3,4-triphosphate (sodium salt)
  • 别名:
    1,3,4-IP3 (sodium salt)|Ins(1,3,4)-P3 (sodium salt)
  • 产品描述:
    The inositol phosphates play a critical role as small, soluble second messengers in transmission of cellular signals.{8672,8344} D-myo-Inositol-1,3,4-triphosphate (Ins(1,3,4)-P3) is one of several different inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels.{8674} The levels of Ins(1,3,4)-P3 are in turn regulated by the levels of cytosolic free calcium.{9102} The receptor-mediated activation of phospholipase C (PLC) can be seen as the initiating event in this cascade, since PLC generates Ins(1,4,5)-P3 which releases calcium from intracellular storage reservoirs, leading to a dramatic but transient increase in the cytosolic concentration of free calcium.{5714}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    486
  • 产品形式:
    A lyophilized powder
  • 存储溶液:
  • 有效期:
    1825
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • 分子式:
    C6H12O15P3 • 3Na
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