产品描述:
Torin 2 is a potent and selective inhibitor of cellular mTOR activity (EC50 = 0.3 nM).{22455} It shows more than 800-fold selectivity for mTOR over PI3K (EC50 = 200 nM) and greater than 100-fold binding selectivity relative to 440 other protein kinases.{22455} Torin 2 has significantly improved bioavailability (54%), metabolic stability, and plasma exposure compared to torin 1 (Item No. 10997).{22455,19694}