产品描述:
Arctigenin is an extract from A. lappa, a burdock plant traditionally used in Japanese Kampo medicine for its antioxidant, anti-inflammatory, antiproliferative, and antiviral activity. At 0.1 μM, arctigenin can block the activation of Akt induced by glucose starvation in pancreatic cancer PANC-1 cells, which is a key process in the tolerance exhibited by cancer cells to glucose starvation.{23767} It has potent in vitro antiviral activities against influenza A virus and shows neuroprotective effects against an experimental mouse model of Japanese encephalitis.{23769,23766} Arctigenin also demonstrates a therapeutic effect in ischemic stroke treatment of middle cerebral artery occluded rats by suppressing microglia activation and decreasing IL-1β and TNF-α expression.{23768}