产品描述:
HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 µM, respectively).{24251} It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 µM).{24251}