产品描述:
MNS is a β-nitrostyrene that blocks and reverses platelet aggregation induced by such triggers as collagen, U-46619 (Item No. 16450), and ADP (IC50 = 1.1, 2.1, and 4.1 µM, respectively).{24470,24469} It reduces tyrosine phosphorylation in stimulated platelets and inhibits recombinant human Syk and Src (IC50 = 2.8 and 27.3 µM, respectively) in vitro.{24470,24471}