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1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC
品牌： Cayman
产品货号： 28153-5 mg
规格： 5 mg

报价：
折后价：

数量： - +
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  • 产品名称:
    1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC
  • 别名:
    16:0(d9) Lyso-PC|16:0-d9/0:0-PC|1-Hexadecanoyl-d9-sn-glycero-3-Phosphatidylcholine|1-Hexadecanoyl-d9-sn-glycero-3-Phosphocholine|PC(16:0-d9/0:0)
  • 产品描述:
    1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-palmitoyl-2-hydroxy-sn-glycero-3-PC (Item No. 10172) by GC- or LC-MS. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine.{11139} It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and phosphorylation of ERK1/2 in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 125 µM.{42919} 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC potentiates the secretion of IL-6, IL-1β, IL-12, and TNF-α in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages when used at concentrations of 0.3 and 1.0 µM.{42920} It increases TGF-β1 production and enhances Foxp3 protein levels in Treg cells in isolated human peripheral blood when used at a concentration of 10 µM.{42921} 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis when administered at a dose of 10 mg/kg.{11693}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    504.7
  • 产品形式:
    A crystalline solid
  • 存储溶液:
  • 有效期:
    730
  • 产地:
    美国
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  • 纯度:
    ≥99% deuterated forms (d1-d9)
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  • CAS号:
    1872379-72-0
  • 分子式:
    C24H41D9NO7P
  • 溶解度:
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